Efficacy of statin therapy in the prevention of atrial fibrillation in patients after coronary artery bypass grafting

Statin medication has shown good results in the prevention of the postoperative atrial fibrillation (AF) after coronary artery bypass grafting (CABG). Objective: To assess the role of statin medication in the prevention of AF after CABG. Material and Methods: A retrospective analysis of 225 medical records of the patients, aged 57.5±7.9 years (mean±SD), who underwent CABG. All patients was divided into two groups. The first group included those patients who did not received statin medication (n=93). We named this group as nSt-patients. Second group included patients who receive statin medication (n=132). We named this group as St-patients. Clinical data on all included patients were obtained in pre-, intra- and postoperative periods. The risk of occurrence of postoperative AF was evaluated using the Cox-regression model. Continuous variables were reported as medians (Me) with inter-quartile ranges (Q1, Q3). Categorical data were presented as percentages. Results: The rate of AF was 29% in nSt-patients and 9% in St-patients (P